Current role and future perspectives of radioiodinated MIBG in the evaluation of dementia with Lewy bodies.

Details

Serval ID
serval:BIB_56284DFFC987
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Current role and future perspectives of radioiodinated MIBG in the evaluation of dementia with Lewy bodies.
Journal
Current radiopharmaceuticals
Author(s)
Treglia G., Ceriani L., Giovanella L.
ISSN
1874-4729 (Electronic)
ISSN-L
1874-4710
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
7
Number
1
Pages
75-78
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Dementia with Lewy bodies (DLB) is the second most common cause of degenerative dementia after Alzheimer's disease (AD). To improve the diagnosis of DLB, the latest diagnostic criteria incorporate findings from neuroimaging studies including sympathetic innervation imaging with iodine-123-metaiodobenzylguanidine (MIBG). According to these criteria a decreased MIBG myocardial uptake is an important finding supporting a clinical diagnosis of DLB. In this review the state of art and future perspectives of sympathetic innervation imaging by using MIBG in the diagnosis of DLB are discussed.

Keywords
3-Iodobenzylguanidine, Biological Transport, Dementia/diagnosis, Dementia/diagnostic imaging, Diagnosis, Differential, Dopamine/chemistry, Humans, Iodine Radioisotopes, Lewy Body Disease/diagnosis, Lewy Body Disease/diagnostic imaging, Radionuclide Imaging, Radiopharmaceuticals, Tomography, Emission-Computed, Single-Photon
Pubmed
Create date
20/08/2017 19:34
Last modification date
20/08/2019 15:10
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