Public health value of fixed-dose combinations in hypertension.

Details

Serval ID
serval:BIB_53327880BE80
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Public health value of fixed-dose combinations in hypertension.
Journal
Blood Pressure. Supplement
Author(s)
Ruilope L.M., Burnier M., Muszbek N., Brown R.E., Keskinaslan A., Ferber P., Harms G.
ISSN
0803-8023 (Print)
ISSN-L
0803-8023
Publication state
Published
Issued date
2008
Volume
1
Pages
5-14
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
It is well documented that reducing blood pressure (BP) in hypertensive individuals reduces the risk of cardiovascular (CV) events. Despite this, many patients with hypertension remain untreated or inadequately treated, and fail to reach the recommended BP goals. Suboptimal BP control, whilst arising from multiple causes, is often due to poor patient compliance and/or persistence, and results in a significant health and economic burden on society. The use of fixed-dose combinations (FDCs) for the treatment of hypertension has the potential to increase patient compliance and persistence. When compared with antihypertensive monotherapies, FDCs may also offer equivalent or better efficacy, and the same or improved tolerability. As a result, FDCs have the potential to reduce both the CV event rates and the non-drug healthcare costs associated with hypertension. When FDCs are adopted for the treatment of hypertension, issues relating to copayment, formulary restrictions and therapeutic reference pricing must be addressed.
Keywords
Antihypertensive Agents/administration & dosage, Antihypertensive Agents/economics, Cost of Illness, Drug Combinations, Drug Costs, Humans, Hypertension/drug therapy, Hypertension/economics, Insurance, Health, Reimbursement, Patient Compliance, Public Health
Pubmed
Web of science
Create date
03/10/2009 7:54
Last modification date
20/08/2019 14:08
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