Lymphocytic interstitial pneumonia in children with AIDS: high-resolution CT findings.

Détails

ID Serval
serval:BIB_51783300F180
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Lymphocytic interstitial pneumonia in children with AIDS: high-resolution CT findings.
Périodique
European Radiology
Auteur(s)
Becciolini V., Gudinchet F., Cheseaux J.J., Schnyder P.
ISSN
0938-7994
Statut éditorial
Publié
Date de publication
2001
Peer-reviewed
Oui
Volume
11
Numéro
6
Pages
1015-10120
Langue
anglais
Notes
Publication types: Journal Article
Résumé
Pulmonary involvement in children with acquired immunodeficiency syndrome (AIDS) represents a wide spectrum of diseases. Among the non-infectious, non-neoplastic affections associated with AIDS, lymphocytic interstitial pneumonia (LIP) is now a well-recognized entity, but its radiological pattern studied with high-resolution computed tomography (HRCT) has rarely been described in children. The aim of this study was to illustrate the HRCT spectrum of pulmonary involvement in children with LIP and to evaluate its usefulness in the early diagnosis of this entity. Twelve children with AIDS, aged 3-9 years (mean age 5 years 7 months), underwent chest radiographs and HRCT. A control group of 7 healthy aged-matched children was also studied in the same conditions. Diagnosis of LIP was based on clinical data and HRCT findings. Eight children of 12 had a reticulonodular pattern on chest radiographs. Two children had normal chest films and two children showed peribronchiolar thickening. High-resolution CT displayed micronodules, 1-3 mm in diameter, with a perilymphatic distribution in all patients. High-resolution CT demonstrated also subpleural nodules in children without reticulonodular opacities on chest radiographs. High-resolution CT is able to define a more specific pattern of abnormalities than conventional chest radiographs in children with LIP, allows an earlier and more confident diagnosis and may be useful for the detection of other pathologies associated with AIDS, such as opportunistic infections or superimposed malignancies.
Mots-clé
Acquired Immunodeficiency Syndrome/radiography, Child, Child, Preschool, Diagnosis, Differential, Female, Humans, Image Enhancement, Lung/radiography, Lung Diseases, Interstitial/radiography, Lymphocytosis/radiography, Male, Sensitivity and Specificity, Tomography, X-Ray Computed
Pubmed
Web of science
Création de la notice
08/04/2008 15:38
Dernière modification de la notice
03/03/2018 17:11
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