Seeking New Approaches to Patients With Small Cell Lung Cancer.

Détails

ID Serval
serval:BIB_50CD91528E2F
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Seeking New Approaches to Patients With Small Cell Lung Cancer.
Périodique
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Meeting
Auteur(s)
Pietanza M.C., Zimmerman S., Peters S., Curran W.J.
ISSN
1548-8756 (Electronic)
ISSN-L
1548-8748
Statut éditorial
Publié
Date de publication
2016
Peer-reviewed
Oui
Volume
35
Pages
e477-82
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
The fundamental approach to the treatment of small cell lung cancer (SCLC) has not changed in the last several decades, with most advances being restricted to improved radiation approaches. The standard first-line chemotherapy regimen in the United States and Europe remains cisplatin or carboplatin plus etoposide in the treatment of limited stage (LS-SCLC) and extensive stage (ES-SCLC) disease. Radiation therapy is administered to those patients with LS-SCLC, whose cancer is confined to the chest in a single tolerable radiation field. This article will summarize a number of exciting observations regarding the biology of SCLC and how a deeper understanding of newly integrated targets and target pathways may lead to new and better therapeutic approaches in the near future.

Mots-clé
Aurora Kinases/antagonists & inhibitors, Aurora Kinases/genetics, Combined Modality Therapy, DNA Methylation/genetics, Epigenesis, Genetic/genetics, Europe, Humans, Molecular Targeted Therapy, Promoter Regions, Genetic/genetics, Protein Kinase Inhibitors/therapeutic use, Proto-Oncogene Proteins c-myc/antagonists & inhibitors, Proto-Oncogene Proteins c-myc/genetics, Small Cell Lung Carcinoma/drug therapy, Small Cell Lung Carcinoma/genetics, Small Cell Lung Carcinoma/pathology, Small Cell Lung Carcinoma/radiotherapy
Pubmed
Création de la notice
14/06/2016 17:07
Dernière modification de la notice
03/03/2018 17:09
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