Insuffisance rénale terminale d'origine lithiasique : fréquence, causes et prévention [Nephrolithiasis-induced ESRD: frequency, causes and prevention].

Details

Serval ID
serval:BIB_4CE77E1D6BD3
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Insuffisance rénale terminale d'origine lithiasique : fréquence, causes et prévention [Nephrolithiasis-induced ESRD: frequency, causes and prevention].
Journal
Néphrologie et Thérapeutique
Author(s)
Jungers P., Joly D., Barbey F., Choukroun G., Daudon M.
ISSN
1769-7255 (Print)
ISSN-L
1769-7255
Publication state
Published
Issued date
2005
Peer-reviewed
Oui
Volume
1
Number
5
Pages
301-310
Language
french
Notes
Publication types: English Abstract ; Journal ArticlePublication Status: ppublish
Abstract
Nephrolithiasis still remains a too frequent - and under-appreciated - cause of end-stage renal disease (ESRD), and this is all the most unfortunate since such an untoward course is now preventable in most cases. Among 1391 patients who started maintenance dialysis at Necker hospital between 1989 and 2000, nephrolithiasis was identified as the cause of ESRD in 45 of them, an overall prevalence of 3.2%. Infection stones accounted for 42.2% of cases, calcium stones for 26.7%, uric acid stones for 17.8% and hereditary diseases for 13.3%. The proportion of nephrolithiasis-associated ESRD declined from 4.7% to 2.2% from the 1989-1991 to the 1998-2000 period, as a result of the decreased incidence of ESRD in patients with infection and calcium nephrolithiasis. Based on our observations and on published reports, it emerges that most cases of nephrolithiasis-associated ESRD were due to sub-optimal management (especially in the case of infection or cystine stones) or to late (or erroneous) etiologic diagnosis, precluding early institution of appropriate therapeutic measures. In particular, several patients with primary hyperoxaluria or 2,8-dihydroxyadeninuria were diagnosed while already on dialysis or after unsuccessful kidney transplantation, due to wrong initial diagnosis. In conclusion, thanks to recent advances in diagnosis and management of stone formers, ESRD should now be prevented in the great majority of patients, at the condition of early etiologic diagnosis based on accurate morphoconstitutional analysis of calculi and metabolic evaluation, and early implementation of appropriate preventive medical treatment.
Keywords
Diagnostic Errors, Female, France/epidemiology, Humans, Kidney Calculi/complications, Kidney Calculi/diagnosis, Kidney Failure, Chronic/epidemiology, Kidney Failure, Chronic/etiology, Male, Retrospective Studies, Risk Factors
Pubmed
Create date
09/02/2012 16:33
Last modification date
20/08/2019 14:01
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