Integration of vascular biology and magnetic resonance imaging in the understanding of atherothrombosis and acute coronary syndromes.

Détails

ID Serval
serval:BIB_4BBAA1DEA664
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Integration of vascular biology and magnetic resonance imaging in the understanding of atherothrombosis and acute coronary syndromes.
Périodique
Journal of Thrombosis and Haemostasis
Auteur(s)
Fuster V., Corti R., Fayad Z.A., Schwitter J., Badimon J.J.
ISSN
1538-7933 (Print)
ISSN-L
1538-7836
Statut éditorial
Publié
Date de publication
2003
Volume
1
Numéro
7
Pages
1410-1421
Langue
anglais
Notes
Publication types: Journal Article ; Review
Résumé
The interaction between the vulnerable atherosclerotic plaque prone to disruption and thrombus formation is the cornerstone of acute coronary syndrome (ACS). Although distinct from one another, the atherosclerotic and thrombotic processes appear to be interdependent, hence the term atherothrombosis. Inflammation is a crucial common pathophysiological mechanism. Overall, the association of plaque vulnerability and ACS has been well documented. Given the multifactorial origin of atherothrombosis the best preventive approach should be aggressive management of all the risk factors. New interventions should be directed toward decreasing vulnerability of the lesions thereby decreasing the risk of ACS.
Mots-clé
Animals, Arteriosclerosis, Endothelium, Vascular/pathology, Female, Heart/anatomy & histology, Heart Diseases/diagnosis, Heart Diseases/pathology, Humans, Inflammation, Magnetic Resonance Imaging/methods, Male, Middle Aged, Models, Biological, Monocytes/metabolism, Myocardium/pathology
Pubmed
Web of science
Création de la notice
07/09/2011 19:55
Dernière modification de la notice
20/08/2019 13:59
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