Catabolite repression control of pyocyanin biosynthesis at an intersection of primary and secondary metabolism in Pseudomonas aeruginosa.
Details
Serval ID
serval:BIB_4B52572A08E0
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Catabolite repression control of pyocyanin biosynthesis at an intersection of primary and secondary metabolism in Pseudomonas aeruginosa.
Journal
Applied and Environmental Microbiology
ISSN
1098-5336 (Electronic)
ISSN-L
0099-2240
Publication state
Published
Issued date
2012
Volume
78
Number
14
Pages
5016-5020
Language
english
Abstract
In Pseudomonas aeruginosa, the catabolite repression control (Crc) protein repressed the formation of the blue pigment pyocyanin in response to a preferred carbon source (succinate) by interacting with phzM mRNA, which encodes a key enzyme in pyocyanin biosynthesis. Crc bound to an extended imperfect recognition sequence that was interrupted by the AUG translation initiation codon.
Keywords
Bacterial Proteins/biosynthesis, Bacterial Proteins/genetics, Catabolite Repression, Codon, Initiator, Gene Expression Regulation, Bacterial, Methyltransferases/genetics, Methyltransferases/metabolism, Pseudomonas aeruginosa/enzymology, Pseudomonas aeruginosa/genetics, Pyocyanine/biosynthesis, Pyocyanine/genetics, Repressor Proteins/genetics, Repressor Proteins/metabolism, Succinic Acid/metabolism
Pubmed
Web of science
Open Access
Yes
Create date
12/02/2013 15:39
Last modification date
20/08/2019 14:59
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