Article: article from journal or magazin.
Antifungal and antibacterial chalcones from Myrica serrata.
Publication types: Journal Article ; Research Support, Non-U.S. Gov't Publication Status: ppublish
The dichloromethane extract of the leaves of Myrica serrata inhibits growth of Cladosporium cucumerinum, Bacillus subtilis, and Escherichia coli on TLC plates. Activity-guided fractionation led the isolation of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone (1), 2',4'-dihydroxy-6'-methoxy-5'-methylchalcone (aurentiacin A) (2), 2',6'-dihydroxy-4'-methoxy-3',5'-dimethyldihydrochalcone (3), 2'-hydroxy-4',6'-dimethoxy-3'-methyldihydrochalcone (4), and 2', 6'-dihydroxy-4'-methoxy-3'-methyldihydrochalcone (5). In addition, the flavanones demethoxymatteucinol (6) and cryptostrobin (7) were also identified.
Anti-Bacterial Agents, Anti-Infective Agents/chemistry, Anti-Infective Agents/isolation & purification, Antifungal Agents/chemistry, Antifungal Agents/isolation & purification, Bacillus subtilis/drug effects, Candida albicans/drug effects, Chalcone/chemistry, Chalcone/isolation & purification, Cladosporium/drug effects, Escherichia coli/drug effects, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests
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