Article: article from journal or magazin.
p53 Gene alterations and p53 protein accumulation in infiltrating ductal breast carcinomas: correlation between immunohistochemical and molecular biology techniques
PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't
One hundred and eighty-eight infiltrating ductal carcinomas of the breast were examined immunohistochemically (IMM) for p53, and the results were compared to those of single strand conformation polymorphism (SSCP). Of the 65 IMM+ cases (35%), 32 showed a genetic alteration in exons 5 to 9. In some of the IMM+
Adult/Age Factors/Aged/Aged,80 and over/Base Sequence/Breast Neoplasms/chemistry/genetics/Pathology/Carcinoma,Ductal,Breast/DNA,Neoplasm/analysis/Exons/Female/Genes,p53/Humans/Immunohistochemistry/Lymphatic Metastasis/Middle Aged/Molecular Sequence Data/Polymerase Chain Reaction/Polymorphism,Genetic/Prognosis/Sensitivity and Specificity/Survival Analysis/Tumor Suppressor Protein p53/Research
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