Early inflammation in the airways of a cystic fibrosis foetus.
Details
Serval ID
serval:BIB_46265D0C1CE1
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Early inflammation in the airways of a cystic fibrosis foetus.
Journal
Journal of Cystic Fibrosis
ISSN
1569-1993[print], 1569-1993[linking]
Publication state
Published
Issued date
2007
Volume
6
Number
4
Pages
304-308
Language
english
Abstract
In cystic fibrosis patients, inflammation is often considered to be secondary to chronic infections. In the present study, we show increased levels of pro-inflammatory proteins in the lungs of a cystic fibrosis foetus compared to the lungs of two normal foetuses. Our findings suggest therefore the existence of an early intrinsic pro-inflammatory state in cystic fibrosis airways.
Keywords
Biological Markers/metabolism, Bronchitis/embryology, Bronchitis/metabolism, Cystic Fibrosis/embryology, Cystic Fibrosis/metabolism, Cytokines/metabolism, Female, Fetal Diseases/metabolism, Fetal Diseases/pathology, Fluorescent Antibody Technique, Gestational Age, Humans, Immunohistochemistry, Lung/metabolism, Lung/pathology, Microscopy, Confocal, NF-kappa B/metabolism, Pregnancy, Pregnancy Outcome
Pubmed
Open Access
Yes
Create date
27/10/2010 9:58
Last modification date
20/08/2019 14:51
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