Early inflammation in the airways of a cystic fibrosis foetus.

Détails

ID Serval
serval:BIB_46265D0C1CE1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Early inflammation in the airways of a cystic fibrosis foetus.
Périodique
Journal of Cystic Fibrosis
Auteur(s)
Verhaeghe C., Delbecque K., de Leval L., Oury C., Bours V.
ISSN
1569-1993[print], 1569-1993[linking]
Statut éditorial
Publié
Date de publication
2007
Volume
6
Numéro
4
Pages
304-308
Langue
anglais
Résumé
In cystic fibrosis patients, inflammation is often considered to be secondary to chronic infections. In the present study, we show increased levels of pro-inflammatory proteins in the lungs of a cystic fibrosis foetus compared to the lungs of two normal foetuses. Our findings suggest therefore the existence of an early intrinsic pro-inflammatory state in cystic fibrosis airways.
Mots-clé
Biological Markers/metabolism, Bronchitis/embryology, Bronchitis/metabolism, Cystic Fibrosis/embryology, Cystic Fibrosis/metabolism, Cytokines/metabolism, Female, Fetal Diseases/metabolism, Fetal Diseases/pathology, Fluorescent Antibody Technique, Gestational Age, Humans, Immunohistochemistry, Lung/metabolism, Lung/pathology, Microscopy, Confocal, NF-kappa B/metabolism, Pregnancy, Pregnancy Outcome
Pubmed
Open Access
Oui
Création de la notice
27/10/2010 9:58
Dernière modification de la notice
08/05/2019 17:56
Données d'usage