Article: article from journal or magazin.
Early inflammation in the airways of a cystic fibrosis foetus.
Journal of Cystic Fibrosis
In cystic fibrosis patients, inflammation is often considered to be secondary to chronic infections. In the present study, we show increased levels of pro-inflammatory proteins in the lungs of a cystic fibrosis foetus compared to the lungs of two normal foetuses. Our findings suggest therefore the existence of an early intrinsic pro-inflammatory state in cystic fibrosis airways.
Biological Markers/metabolism, Bronchitis/embryology, Bronchitis/metabolism, Cystic Fibrosis/embryology, Cystic Fibrosis/metabolism, Cytokines/metabolism, Female, Fetal Diseases/metabolism, Fetal Diseases/pathology, Fluorescent Antibody Technique, Gestational Age, Humans, Immunohistochemistry, Lung/metabolism, Lung/pathology, Microscopy, Confocal, NF-kappa B/metabolism, Pregnancy, Pregnancy Outcome
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