Article: article from journal or magazin.
Infectious diseases not immune to genome-wide association.
Publication types: Comment ; News
Two genome-wide association studies for meningococcal disease and tuberculosis identify new loci associated with susceptibility to these infectious diseases. They highlight a role for the acquired and innate immune systems in host control of several human pathogens and demonstrate that denser genotyping platforms and population-specific reference panels are necessary for genetic studies in African populations.
Africa, Communicable Diseases/genetics, Communicable Diseases/immunology, Disease Susceptibility/immunology, Genetic Predisposition to Disease, Genetics, Population/trends, Genome-Wide Association Study/trends, Genome-Wide Association Study/utilization, Host-Pathogen Interactions/genetics, Host-Pathogen Interactions/immunology, Humans, Immunity, Innate/genetics, Infectious Disease Medicine/methods, Infectious Disease Medicine/trends
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