Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
Uptake of In-111 pentetreotide by normally functioning nodular goiters.
Clinical Nuclear Medicine
Publication types: Case Reports ; Journal ArticlePublication Status: ppublish
After the intravenous administration of a radiolabeled somatostatin analogue (octreotide), normal thyroid and neoplastic and nonneoplastic thyroid lesions can be visualized. The authors present the cases of two patients who underwent somatostatin receptor scintigraphy (SSRS) using In-111 pentetreotide: one for the study of suspected paraneoplastic ACTH hypersecretion, and the other for a restaging of breast carcinoma with neuroendocrine features. In both patients, SSRS revealed increased uptake in the thyroid, corresponding to "cold" nodules on Tc-99m pertechnetate imaging. Cytologic and histologic examinations showed the typical features of thyroid goiters without lymphocytic infiltration.
Adenoma/radionuclide imaging, Adrenocorticotropic Hormone/secretion, Biopsy, Needle, Breast Neoplasms/radionuclide imaging, Carcinoma/radionuclide imaging, Female, Goiter, Nodular/pathology, Goiter, Nodular/radionuclide imaging, Humans, Indium Radioisotopes/administration & dosage, Injections, Intravenous, Middle Aged, Neoplasm Staging, Neuroendocrine Tumors/radionuclide imaging, Paraneoplastic Syndromes/radionuclide imaging, Pituitary Neoplasms/radionuclide imaging, Radiopharmaceuticals/administration & dosage, Receptors, Somatostatin, Sodium Pertechnetate Tc 99m, Somatostatin/administration & dosage, Somatostatin/analogs & derivatives, Thyroid Gland/radionuclide imaging, Thyroid Nodule/pathology, Thyroid Nodule/radionuclide imaging
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