Article: article from journal or magazin.
Traitement des fibroses pulmonaires idiopathiques [Treatment of idiopathic pulmonary fibrosis]
Schweizerische Medizinische Wochenschrift
Idiopathic pulmonary fibrosis still has to be diagnosed by elimination. Neoplasm, toxic treatments, collagen vascular disease, professional exposure or diagnosis such as sarcoidosis have to be ruled out. The repercussions on gas exchange are the most reliable indications of the severity of the disease, the pulmonary function test or chest x-rays alone being often misleading. Transbronchic biopsies, thoracotomy or thoracoscopies provide a precise diagnosis. In many cases only broncho-alveolar lavage and a high resolution CT-scan are performed to rule out infection or tumor and to assess the inflammatory state of the disease. Due to the often poor prognosis of this disease and its often poor response to steroids, the role of cytostatic drugs, cyclosporine and colchicine, and of pulmonary graft is discussed.
Azathioprine/therapeutic use, Colchicine/therapeutic use, Cyclophosphamide/therapeutic use, Cyclosporine/therapeutic use, Diagnosis, Differential, Humans, Lung Diseases/diagnosis, Lung Transplantation, Prednisone/therapeutic use, Pulmonary Fibrosis/diagnosis, Pulmonary Fibrosis/physiopathology, Pulmonary Gas Exchange, Radiography, Thoracic, Respiratory Function Tests
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