Dual-energy computed tomographic imaging of pulmonary hypertension.

Details

Serval ID
serval:BIB_3A73B7A3E89A
Type
Article: article from journal or magazin.
Publication sub-type
Editorial
Collection
Publications
Institution
Title
Dual-energy computed tomographic imaging of pulmonary hypertension.
Journal
Swiss medical weekly
Author(s)
Hachulla A.L., Lador F., Soccal P.M., Montet X., Beghetti M.
ISSN
1424-3997 (Electronic)
ISSN-L
0036-7672
Publication state
Published
Issued date
2016
Peer-reviewed
Oui
Volume
146
Pages
w14328
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Abstract
Dual-energy computed tomography (DECT) angiography of the chest provides a combined morphological and functional analysis of the lung, usually obtained in a single acquisition without extra radiation or injection of extra intravenous iodine contrast. The parenchymal iodine maps generated by DECT are well correlated with scintigraphy, and are becoming an essential tool for evaluating patients with pulmonary vascular diseases. With a single DECT acquisition, complete imaging of pulmonary hypertension is now available, displaying vascular anatomy, parenchymal morphology and functional assessment. Triangular pulmonary perfusion defects in chronic thromboembolic pulmonary hypertension may be clearly analysed even in the presence of distal arterial occlusion. Perfusion heterogeneities seen in patients with pulmonary arterial hypertension reflect mosaic perfusion and may be helpful for the diagnosis, severity assessment and prognosis of the disease. Vascular or parenchymal abnormalities can also be analysed with perfusion defects to determine their aetiology. Pulmonary arterial hypertension due to congenital heart disease can be assessed with a single DECT, even in the neonatal population. Furthermore, new applications are emerging with ventilation imaging or myocardial perfusion imaging obtained by DECT and should be considered. In conclusion, DECT of the thorax enables the simultaneous and noninvasive assessment of vascular anatomy, parenchymal morphology and functional pulmonary imaging in various groups of PH.
Keywords
Computed Tomography Angiography/methods, Heart Diseases/diagnostic imaging, Humans, Hypertension, Pulmonary/diagnostic imaging, Thorax/diagnostic imaging
Pubmed
Web of science
Open Access
Yes
Create date
10/01/2019 16:44
Last modification date
11/10/2019 5:26
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