Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Pregnancy and breastfeeding in patients with Crohn's disease
Crohn's disease commonly affects women of childbearing age. Available data on Crohn's disease and pregnancy show that women with Crohn's disease can expect to conceive successfully, carry to term and deliver a healthy baby. Control of disease activity before conception and during pregnancy is critical, to optimize both maternal and fetal health. Generally speaking, pharmacological therapy for Crohn's disease during pregnancy is similar to pharmacological therapy for nonpregnant patients. Patients maintained in remission by way of pharmacological therapy should continue it throughout their pregnancy. Sulfasalazine, mesalazine and corticosteroids are safe, azathioprine and 6-mercaptopurine are reasonably safe with few discordant data, infliximab seems safe as well, whereas methotrexate is contraindicated during pregnancy. During breastfeeding, mesalazine and prednisone are considered safe, azathioprine/6-mercaptopurine, budesonide and infliximab probably safe and methotrexate is contraindicated. [Ed.]
Anti-Infective Agents, Anti-Infective Agents/therapeutic use, Anti-Inflammatory Agents, Non-Steroidal, Anti-Inflammatory Agents, Non-Steroidal/therapeutic use, Breast Feeding, Crohn Disease, Crohn Disease/drug therapy, Drug Therapy, Combination, Female, Glucocorticoids, Glucocorticoids/therapeutic use, Humans, Immunologic Factors/therapeutic use, Mesalamine, Pregnancy, Pregnancy Complications, Pregnancy Complications/drug therapy, Pregnancy Outcome, Safety
Web of science
Last modification date