Suivi thérapeutique des médicaments (I). Les principes [Principles of therapeutic drug monitoring]

Détails

ID Serval
serval:BIB_3645892D4B54
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Suivi thérapeutique des médicaments (I). Les principes [Principles of therapeutic drug monitoring]
Périodique
Revue medicale suisse
Auteur(s)
Widmer N., Csajka C., Werner D., Grouzmann E., Decosterd L.A., Eap C.B., Biollaz J., Buclin T.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
16/07/2008
Peer-reviewed
Oui
Volume
4
Numéro
165
Pages
1644-1648
Langue
français
Notes
Publication types: English Abstract ; Journal Article ; Review
Publication Status: ppublish
Résumé
Requesting a blood level measurement of a drug is part of the global approach known as "Therapeutic Drug Monitoring". Diverse situations require this monitoring approach, such as inadequate response to treatment or organ failure. Every drug however does not possess all the characteristics for a TDM program. The therapeutic range of a TDM drug has indeed to be narrow and its interindividual pharmacokinetic variability to be wide. As the development of new drugs is currently slowing down, the precise management of existing treatments certainly deserves progress, but needs however to be applied rationally, starting from a valid indication to blood sampling, and ending with a sound dosage adaptation decision.

Mots-clé
Anti-Bacterial Agents/administration & dosage, Anti-Bacterial Agents/blood, Anti-Bacterial Agents/pharmacokinetics, Anti-Retroviral Agents/administration & dosage, Anti-Retroviral Agents/blood, Anti-Retroviral Agents/pharmacokinetics, Anticonvulsants/administration & dosage, Anticonvulsants/blood, Anticonvulsants/pharmacokinetics, Antineoplastic Agents/administration & dosage, Antineoplastic Agents/blood, Antineoplastic Agents/pharmacokinetics, Antiparasitic Agents/administration & dosage, Antiparasitic Agents/blood, Antiparasitic Agents/pharmacokinetics, Antitubercular Agents/administration & dosage, Antitubercular Agents/blood, Antitubercular Agents/pharmacokinetics, Cardiovascular Agents/administration & dosage, Cardiovascular Agents/blood, Cardiovascular Agents/pharmacokinetics, Dose-Response Relationship, Drug, Drug Monitoring/methods, Humans, Immunosuppressive Agents/administration & dosage, Immunosuppressive Agents/blood, Immunosuppressive Agents/pharmacokinetics, Pharmaceutical Preparations/administration & dosage, Pharmaceutical Preparations/blood, Product Surveillance, Postmarketing, Psychotropic Drugs/administration & dosage, Psychotropic Drugs/blood, Psychotropic Drugs/pharmacokinetics
Pubmed
Création de la notice
10/10/2017 11:12
Dernière modification de la notice
21/08/2019 5:33
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