Clinical evaluation of the lysis-centrifugation blood culture system for the detection of fungemia and comparison with a conventional biphasic broth blood culture system

Details

Serval ID
serval:BIB_3511D1160104
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Clinical evaluation of the lysis-centrifugation blood culture system for the detection of fungemia and comparison with a conventional biphasic broth blood culture system
Journal
Journal of Clinical Microbiology
Author(s)
Bille  J., Edson  R. S., Roberts  G. D.
ISSN
0095-1137
Publication state
Published
Issued date
02/1984
Peer-reviewed
Oui
Volume
19
Number
2
Pages
126-8
Notes
Comparative Study
Journal Article --- Old month value: Feb
Abstract
In a comparative fungal blood culture study, a lysis-centrifugation system (Isolator; Du Pont Co., Wilmington, Del.) detected 89% of all episodes of fungemia; the lysis-centrifugation system detected fungemia exclusively or significantly earlier than did a biphasic brain heart infusion bottle system 83% of the time. The lysis-centrifugation system was particularly useful in the early detection of fungemia caused by Candida tropicalis and Candida glabrata. In 53% of the clinically significant episodes, the earlier detection was directly helpful in the management of patients with fungemia. High-magnitude candidemia (greater than 5 CFU/ml of blood) was significantly associated with the presence of an infected intravascular catheter and with Candida species other than Candida albicans. The lysis-centrifugation system was sensitive in the detection of fungemia during the monitoring of patients receiving antifungal agents or after removal of an infected intravascular catheter.
Keywords
Candidiasis/blood/microbiology Centrifugation Culture Media Evaluation Studies as Topic Humans *Microbiological Techniques Mycoses/*blood/microbiology
Pubmed
Web of science
Create date
11/02/2008 12:40
Last modification date
20/08/2019 13:22
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