Hépatite D:oubliée mais pas disparue [Hepatitis D: forgotten but not gone].

Details

Serval ID
serval:BIB_28ED6BBD6620
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Hépatite D:oubliée mais pas disparue [Hepatitis D: forgotten but not gone].
Journal
Revue Médicale Suisse
Author(s)
Moradpour D., Negro F.
ISSN
1660-9379[print], 1660-9379[linking]
Publication state
Published
Issued date
2010
Volume
6
Number
261
Pages
1656-1659
Language
french
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Abstract
Hepatitis D virus (HDV) is a subviral agent which depends on the envelope proteins (HBsAg) of hepatitis B virus (HBV). Therefore, hepatitis D is observed only in patients infected with HBV. Chronic hepatitis D is the least frequent albeit most severe form of chronic viral hepatitis. A resurgence of chronic hepatitis D has been observed in Northern and Central Europe, mainly due to immigration of patients from regions with high prevalence. Every HBsAg-positive patient should be screened for concurrent HDV infection. Standard treatment consists of pegylated interferon-alpha for at least one year. Sustained virological response rates are approximately 20%. Liver transplantation should be considered in patients with advanced cirrhosis or limited hepatocellular carcinoma. Preventive measures for hepatitis D are the same as for hepatitis B.
Keywords
Antiviral Agents/therapeutic use, European Union/statistics & numerical data, Hepatitis B/complications, Hepatitis D/diagnosis, Hepatitis D/epidemiology, Hepatitis D, Chronic, Hepatitis Delta Virus/isolation & purification, Humans, Interferon Alfa-2a/therapeutic use, Interferon Alfa-2b/therapeutic use, Liver Transplantation, Polyethylene Glycols/therapeutic use, Prevalence, World Health
Pubmed
Create date
05/01/2011 15:53
Last modification date
20/08/2019 13:08
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