Infection after fracture fixation: Current surgical and microbiological concepts.

Détails

ID Serval
serval:BIB_25D8472157DC
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Infection after fracture fixation: Current surgical and microbiological concepts.
Périodique
Injury
Auteur(s)
Metsemakers W.J., Kuehl R., Moriarty T.F., Richards R.G., Verhofstad MHJ, Borens O., Kates S., Morgenstern M.
ISSN
1879-0267 (Electronic)
ISSN-L
0020-1383
Statut éditorial
Publié
Date de publication
03/2018
Peer-reviewed
Oui
Volume
49
Numéro
3
Pages
511-522
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
One of the most challenging complications in trauma surgery is infection after fracture fixation (IAFF). IAFF may result in permanent functional loss or even amputation of the affected limb in patients who may otherwise be expected to achieve complete, uneventful healing. Over the past decades, the problem of implant related bone infections has garnered increasing attention both in the clinical as well as preclinical arenas; however this has primarily been focused upon prosthetic joint infection (PJI), rather than on IAFF. Although IAFF shares many similarities with PJI, there are numerous critical differences in many facets including prevention, diagnosis and treatment. Admittedly, extrapolating data from PJI research to IAFF has been of value to the trauma surgeon, but we should also be aware of the unique challenges posed by IAFF that may not be accounted for in the PJI literature. This review summarizes the clinical approaches towards the diagnosis and treatment of IAFF with an emphasis on the unique aspects of fracture care that distinguish IAFF from PJI. Finally, recent developments in anti-infective technologies that may be particularly suitable or applicable for trauma patients in the future will be briefly discussed.
Mots-clé
Anti-Infective Agents/therapeutic use, Biofilms/drug effects, Fracture Fixation/adverse effects, Fractures, Bone/microbiology, Fractures, Bone/surgery, Humans, Osteomyelitis/drug therapy, Osteomyelitis/microbiology, Practice Guidelines as Topic, Prosthesis-Related Infections/drug therapy, Prosthesis-Related Infections/microbiology, Antibiotic therapy, Biofilm, Complications, Implant-related infection, Infected non-union, Infection after fracture fixation
Pubmed
Web of science
Création de la notice
28/09/2016 17:15
Dernière modification de la notice
20/08/2019 13:04
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