Characterization of a Bacillus subtilis thermosensitive teichoic acid-deficient mutant: gene mnaA (yvyH) encodes the UDP-N-acetylglucosamine 2-epimerase.
Details
Serval ID
serval:BIB_25985
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Characterization of a Bacillus subtilis thermosensitive teichoic acid-deficient mutant: gene mnaA (yvyH) encodes the UDP-N-acetylglucosamine 2-epimerase.
Journal
Journal of Bacteriology
ISSN
0021-9193 (Print)
ISSN-L
0021-9193
Publication state
Published
Issued date
2002
Volume
184
Number
15
Pages
4316-4320
Language
english
Abstract
The Bacillus subtilis thermosensitive mutant ts-21 bears two C-G-->T-A transitions in the mnaA gene. At the nonpermissive temperature it is characterized by coccoid cell morphology and reduced cell wall phosphate content. MnaA converts UDP-N-acetylglucosamine into UDP-N-acetylmannosamine, a precursor of the teichoic acid linkage unit.
Keywords
Amino Acid Sequence, Bacillus subtilis/genetics, Bacillus subtilis/metabolism, Carbohydrate Epimerases/genetics, Carbohydrate Epimerases/metabolism, Cell Wall/metabolism, Escherichia coli Proteins, Molecular Sequence Data, Mutation, Phosphates/metabolism, Sequence Alignment, Teichoic Acids/genetics, Teichoic Acids/metabolism, Temperature
OAI-PMH
Pubmed
Web of science
Open Access
Yes
Create date
19/11/2007 13:22
Last modification date
20/08/2019 14:04
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