Temporal trends in adoption and outcomes of transcatheter aortic valve implantation: a SwissTAVI Registry analysis.

Details

Serval ID
serval:BIB_2585BF5A1AD4
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Temporal trends in adoption and outcomes of transcatheter aortic valve implantation: a SwissTAVI Registry analysis.
Journal
European heart journal. Quality of care & clinical outcomes
Author(s)
Stortecky S., Franzone A., Heg D., Tueller D., Noble S., Pilgrim T., Jeger R., Toggweiler S., Ferrari E., Nietlispach F., Taramasso M., Maisano F., Grünenfelder J., Muller O., Huber C., Roffi M., Carrel T., Wenaweser P., Windecker S.
ISSN
2058-1742 (Electronic)
ISSN-L
2058-1742
Publication state
Published
Issued date
01/07/2019
Peer-reviewed
Oui
Volume
5
Number
3
Pages
242-251
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
To describe temporal trends in adoption and performance of transcatheter aortic valve implantation (TAVI) in Switzerland over a period of 5 years.
Between 2011 and 2015, a total of 3493 patients were consecutively included in the SwissTAVI Registry (NCT01368250) and analysed for the purpose of this study. The primary outcome measure was all-cause mortality at 1 year after TAVI. Over the 5-year period, a six-fold increase in the number of procedures was observed, whereas the baseline surgical risk estimated by the Society of Thoracic Surgeon (STS) score declined (from 6.8 ± 4.4% to 4.6 ± 3.6, P < 0.001). Overall, 1-year mortality amounted to 12.8%; mortality was highest in the first annual cohorts (14.6%, 14.8%, and 15.9% in 2011, 2012, and 2013, respectively) and decreased to 13.4% in 2014 and 9.7% in 2015. While rates of cerebrovascular events, peri-procedural myocardial infarction, moderate/severe paravalvular regurgitation, and Stage 3 acute kidney injury did not significantly change over time, a significant reduction in life threatening or major bleeding was noted at 30-day follow-up during the latest compared with earlier years of recruitment.
This long-term recruitment analysis of a national TAVI registry showed rapid adoption paralleled by a progressive decrease of patients' baseline risk profile. Early and late survival significantly improved over time as did the rate of life threatening or major bleeding.
Keywords
Aortic stenosis, Mortality, Transcatheter aortic valve implantation, Trends
Pubmed
Create date
17/10/2018 8:21
Last modification date
26/08/2020 5:22
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