IFNα Potentiates Immune-Checkpoint Blockade by Rewiring Metabolic Cross-talk.

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Serval ID
serval:BIB_255996E55B3C
Type
Article: article from journal or magazin.
Publication sub-type
Editorial
Collection
Publications
Institution
UNIL/CHUV
Title
IFNα Potentiates Immune-Checkpoint Blockade by Rewiring Metabolic Cross-talk.
Journal
Cancer discovery
Author(s)
Kao K.C., Jaccard A., Ho P.C.
ISSN
2159-8290 (Electronic)
ISSN-L
2159-8274
Publication state
Published
Issued date
06/07/2022
Peer-reviewed
Oui
Volume
12
Number
7
Pages
1615-1616
Language
english
Notes
Publication types: Editorial ; Comment
Publication Status: ppublish
Abstract
In this issue, Hu and colleagues unveil that IFNα administration combined with anti-PD-1 therapy can potentiate murine and human CD8+ T-cell antitumor response in hepatocellular carcinoma, highlighting a novel therapeutic strategy for hepatocellular carcinoma. See related article by Hu et al., p. 1718 (6) .
Keywords
Animals, Carcinoma, Hepatocellular/drug therapy, Glucose, Humans, Immune Checkpoint Inhibitors, Immunotherapy, Liver Neoplasms/drug therapy, Mice, Tumor Microenvironment
OAI-PMH
oai:serval.unil.ch:BIB_255996E55B3C
DOI
10.1158/2159-8290.CD-22-0472
Pubmed
35791695
Web of science
000837831600001
Create date
19/07/2022 14:25
Last modification date
03/06/2023 6:51
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