Know thy enemy: Why are tumor-infiltrating regulatory T cells so deleterious?
Details
State: Public
Version: author
Serval ID
serval:BIB_23405BBB539D
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Know thy enemy: Why are tumor-infiltrating regulatory T cells so deleterious?
Journal
Oncoimmunology
ISSN
2162-4011 (Print)
Publication state
Published
Issued date
2012
Volume
1
Number
4
Pages
575-577
Language
english
Notes
Publication types: JOURNAL ARTICLE Publication Status: ppublish. pdf type: AUTHOR'S VIEW
Abstract
We recently described hypoxia as one of the leading mechanism for the recruitment of regulatory T cells (Treg) through CCL28 chemokine in ovarian cancer. Treg promote progression of cancer through tumor-specific immune paralysis but also reprogramming of angiogenesis. We review these mechanisms and discuss the challenges and opportunities for therapy targeting Treg.
Pubmed
Web of science
Create date
14/10/2014 12:42
Last modification date
20/08/2019 14:00
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