Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Know thy enemy: Why are tumor-infiltrating regulatory T cells so deleterious?
Publication types: JOURNAL ARTICLE Publication Status: ppublish. pdf type: AUTHOR'S VIEW
We recently described hypoxia as one of the leading mechanism for the recruitment of regulatory T cells (Treg) through CCL28 chemokine in ovarian cancer. Treg promote progression of cancer through tumor-specific immune paralysis but also reprogramming of angiogenesis. We review these mechanisms and discuss the challenges and opportunities for therapy targeting Treg.
Web of science
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