Article: article from journal or magazin.
An LC/DAD-UV/MS method for the rapid detection of aristolochic acid in plant preparations.
Publication types: Letter ; Research Support, Non-U.S. Gov't Publication Status: ppublish
A new method using direct on-line coupling between HPLC and UV-DAD/MS was developed for the rapid detection of aristolochic acid I in plant preparations. The use of both UV-DAD and MS detectors enables this method to be very selective. A ng range detection limit was determined for both UV and MS detections. A quantitative determination of aristolochic acid I in plant preparations was achieved using UV and MS detection. A thin layer chromatography assay was also developed for the preliminary detection of aristolochic acid I in complex mixtures.
Aristolochia, Aristolochic Acids/chemistry, Aristolochic Acids/isolation & purification, Chromatography/methods, Chromatography, Liquid/methods, Chromatography, Thin Layer/methods, Mass Spectrometry/methods, Molecular Structure, Plant Extracts/chemistry, Plant Extracts/isolation & purification, Plant Leaves/chemistry, Plant Stems/chemistry, Ultraviolet Rays
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