Comparison of analytical performances of the Roche Cobas 6800 CT/NG assay with the Abbott m2000 Real Time CT/NG assay for detecting Chlamydia trachomatis and Neisseria gonorrhoeae.

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Serval ID
serval:BIB_232EBDD8FD6C
Type
Article: article from journal or magazin.
Collection
Publications
Institution
UNIL/CHUV
Title
Comparison of analytical performances of the Roche Cobas 6800 CT/NG assay with the Abbott m2000 Real Time CT/NG assay for detecting Chlamydia trachomatis and Neisseria gonorrhoeae.
Journal
Journal of medical microbiology
Author(s)
Cherkaoui A., Renzi G., Mombelli M., Jaton K., Yerly S., Vuilleumier N., Schrenzel J.
ISSN
1473-5644 (Electronic)
ISSN-L
0022-2615
Publication state
Published
Issued date
02/2019
Peer-reviewed
Oui
Volume
68
Number
2
Pages
197-200
Language
english
Notes
Publication types: Comparative Study ; Journal Article
Publication Status: ppublish
Abstract
The Roche Cobas 6800 CT/NG assay was compared to the Abbott m2000 Real Time CT/NG assay for detecting Chlamydia trachomatis and Neisseria gonorrhoeae in 714 specimens referred to the bacteriology laboratory at Geneva University Hospitals, between November 2017 and March 2018, and in nine external quality controls for molecular diagnostics (seven from QCMD Glasgow and two from UK NEQAS). For C. trachomatis, the sensitivity of C6800 compared to m2000 was 100 % (95 % confidence interval [CI], 97.5 to 100 %), the specificity was 99.1 % (95 % CI, 98.0 to 99.7 %). For N. gonorrhoeae, the sensitivity of the C6800 compared to m2000 was 100 % (95 % CI, 90.5 to 100 %), whereas the specificity was 99.7 % (95 % CI, 98.9 to 99.9 %). The C6800 CT/NG assay appears to perform with great accuracy the detection of C. trachomatis and N. gonorrhoeae.
Keywords
Adolescent, Adult, Aged, Aged, 80 and over, Anal Canal/microbiology, Child, Chlamydia trachomatis/genetics, Chlamydia trachomatis/isolation & purification, Female, Humans, Male, Middle Aged, Neisseria gonorrhoeae/genetics, Neisseria gonorrhoeae/isolation & purification, Oropharynx/microbiology, Predictive Value of Tests, Prospective Studies, Real-Time Polymerase Chain Reaction/standards, Rectum/microbiology, Retrospective Studies, Sensitivity and Specificity, Urine/microbiology, Vagina/microbiology, Young Adult, Abbott m2000, Chlamydia trachomatis, Cobas 6800, Neisseria gonorrhoeae
OAI-PMH
oai:serval.unil.ch:BIB_232EBDD8FD6C
DOI
10.1099/jmm.0.000909
Pubmed
30605081
Web of science
000457872000012
Create date
06/02/2019 11:39
Last modification date
20/08/2019 14:00
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