Gefahrliche Interaktionen zwischen Amiodaron und Antiarrhythmika der Klasse I. [Harmful interactions of amiodarone and class I anti-arrhythmia agents]
Details
Serval ID
serval:BIB_2210BB1C6AED
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Gefahrliche Interaktionen zwischen Amiodaron und Antiarrhythmika der Klasse I. [Harmful interactions of amiodarone and class I anti-arrhythmia agents]
Journal
Schweizerische Medizinische Wochenschrift
ISSN
0036-7672 (Print)
Publication state
Published
Issued date
11/1982
Volume
112
Number
45
Pages
1585-7
Notes
English Abstract
Journal Article --- Old month value: Nov 6
Journal Article --- Old month value: Nov 6
Abstract
Six patients treated with a combination of amiodarone and class I antiarrhythmic agents for a minor arrhythmia developed atypical ventricular tachycardia "en torsades de pointe". All patients had QT-interval prolongation in the ECG. Combined administration of quinidine and amiodarone in a normal volunteer resulted in an increase in plasma quinidine concentration and in QT prolongation, thus confirming the clinical observation of a clinically relevant interaction between the two drugs.
Keywords
Adult
Aged
Amiodarone/administration & dosage/*adverse effects
Anti-Arrhythmia Agents/administration & dosage/*adverse effects
Arrhythmia/drug therapy
Benzofurans/*adverse effects
Drug Interactions
Drug Therapy, Combination
Electrocardiography
Female
Humans
Male
Middle Aged
Quinidine/administration & dosage/adverse effects
Tachycardia/*chemically induced/etiology
Pubmed
Web of science
Create date
15/02/2008 12:28
Last modification date
20/08/2019 13:58