Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
Chronic relapsing neuropathy associated with Castleman's disease (angiofollicular lymph node hyperplasia)
Case Reports Journal Article
We report a 17-year-old patient who presented a chronic relapsing sensorimotor demyelinating neuropathy with 6 relapses over a 7-year period, preceding by 4 years the diagnosis of a multicentric angiofollicular lymph node hyperplasia. A role for Epstein-Barr virus (EBV) as a trigger of the neuropathy may be suggested by the presence of EBV DNA in the biopsied abdominal abdominal adenopathies. This unusual reported association seems to have a better prognosis than the known chronic progressive form of neuropathy associated with Castleman's disease and the Crow-Fukase syndrome.
Adolescent Asthenia/etiology Biopsy Chronic Disease DNA, Viral/analysis Demyelinating Diseases/*complications/pathology/virology Electrophysiology Giant Lymph Node Hyperplasia/*complications/pathology Herpesvirus 4, Human/genetics/isolation & purification Humans Lymph Nodes/pathology/virology Male Mesentery Recurrence Sural Nerve/pathology
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