Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
Delayed generalized allergic reactions to corticosteroids
A 37-year-old patient presented with a severe allergic local reaction upon inhalation of budesonide for asthma. Skin tests were positive for budesonide and amcinonide (group B) and elicited a strong local reaction and a disseminated macular exanthema. Corticosteroids from other groups were well tolerated. A 38-year-old male patient had first an allergic contact dermatitis to topically applied prednisolone acetate and then a disseminated eczematous exanthema upon oral intake of prednisone. A delayed-type sensitization to corticosteroids from group A such as hydrocortisone, prednisone and tixocortol pivalate was identified. A detailed diagnosis in patients with allergic reactions to corticosteroids is crucial with regard to their use in emergency therapy.
Adrenal Cortex Hormones/*adverse effects/therapeutic use Adult Asthma/drug therapy Budesonide/adverse effects/therapeutic use Dermatitis/drug therapy Drug Eruptions/etiology Humans Hypersensitivity, Delayed/*chemically induced/pathology Male Patch Tests Prednisolone/adverse effects/therapeutic use Skin/drug effects/pathology
Web of science
Last modification date