Article: article from journal or magazin.
Sequence analysis of the 308 degrees to 311 degrees segment of the Bacillus subtilis 168 chromosome, a region devoted to cell wall metabolism, containing non-coding grey holes which reveal chromosomal rearrangements.
Publication types: Comparative Study ; Journal Article
The 29.71 kb chromosomal region of Bacillus subtilis 168 extending from 308 degrees to 311 degrees contains 18 ORFs. Functions of most of these ORFs were identified and associated with cell wall metabolism. Sequences of two non-coding regions of 0.7 and 2.2 kb flanking the ggaAB operon involved in the synthesis of poly(3-O-beta-D-glucopyranosyl N-acetylgalactosamine 1-phosphate), a minor teichoic acid, correspond to five degenerate segments of neighbouring protein-coding regions. We discuss the possibility that such grey holes are indicative of a chromosomal rearrangement which could have arisen from horizontal gene transfer.
Bacillus subtilis, Base Sequence, Cell Wall, Chromosomes, Bacterial, DNA, Bacterial, Gene Rearrangement, Genes, Bacterial, Molecular Sequence Data, Multigene Family, Nucleic Acid Conformation, Open Reading Frames, Operon, Regulatory Sequences, Nucleic Acid, Repetitive Sequences, Nucleic Acid, Sequence Analysis, DNA, Sequence Homology, Nucleic Acid
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