Comparison of different positron emission tomography tracers in patients with recurrent medullary thyroid carcinoma: our experience and a review of the literature.

Details

Serval ID
serval:BIB_1764C14F7775
Type
Article: article from journal or magazin.
Collection
Publications
Title
Comparison of different positron emission tomography tracers in patients with recurrent medullary thyroid carcinoma: our experience and a review of the literature.
Journal
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer
Author(s)
Treglia G., Castaldi P., Villani M.F., Perotti G., Filice A., Ambrosini V., Cremonini N., Versari A., Fanti S., Giordano A., Rufini V.
ISSN
0080-0015 (Print)
ISSN-L
0080-0015
Publication state
Published
Issued date
2013
Peer-reviewed
Oui
Volume
194
Pages
385-393
Language
english
Notes
Publication types: Comparative Study ; Journal Article ; Review
Publication Status: ppublish
Abstract
Several morphological and functional imaging techniques are usually used to detect residual/recurrent medullary thyroid carcinoma (MTC) with variable results; currently, there is growing interest in positron emission tomography (PET) methodology. Herein, we report our experience of and a literature review about the comparison of different positron emission tomography (PET) tracers in patients with residual/recurrent MTC. (18)F-DOPA PET/CT seems to be the most useful imaging method to detect recurrent MTC lesions, performing better than (18)F-FDG and (68)Ga-somatostatin analogs PET/CT. (18)F-FDG may complement (18)F-DOPA in patients with aggressive tumors. (68)Ga-somatostatin analogs PET/CT may be useful to select patients who could benefit from radioreceptor therapy. The information provided by the various PET tracers reflects different metabolic pathways, and may help to select the most appropriate treatment.

Keywords
Adult, Aged, Aged, 80 and over, Carcinoma, Neuroendocrine, Dihydroxyphenylalanine/analogs & derivatives, Female, Fluorodeoxyglucose F18, Humans, Male, Middle Aged, Multimodal Imaging/methods, Neoplasm Recurrence, Local/diagnostic imaging, Positron-Emission Tomography, Radiopharmaceuticals, Thyroid Neoplasms/diagnostic imaging, Tomography, X-Ray Computed
Pubmed
Create date
20/08/2017 20:51
Last modification date
20/08/2019 12:47
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