Sexually antagonistic genetic variation for fitness in red deer.

Détails

ID Serval
serval:BIB_16F1C63E22C0
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Sexually antagonistic genetic variation for fitness in red deer.
Périodique
Nature
Auteur(s)
Foerster K., Coulson T., Sheldon B.C., Pemberton J.M., Clutton-Brock T.H., Kruuk L.E.
ISSN
1476-4687[electronic]
Statut éditorial
Publié
Date de publication
2007
Volume
447
Numéro
7148
Pages
1107-1110
Langue
anglais
Résumé
Evolutionary theory predicts the depletion of genetic variation in natural populations as a result of the effects of selection, but genetic variation is nevertheless abundant for many traits that are under directional or stabilizing selection. Evolutionary geneticists commonly try to explain this paradox with mechanisms that lead to a balance between mutation and selection. However, theoretical predictions of equilibrium genetic variance under mutation-selection balance are usually lower than the observed values, and the reason for this is unknown. The potential role of sexually antagonistic selection in maintaining genetic variation has received little attention in this debate, surprisingly given its potential ubiquity in dioecious organisms. At fitness-related loci, a given genotype may be selected in opposite directions in the two sexes. Such sexually antagonistic selection will reduce the otherwise-expected positive genetic correlation between male and female fitness. Both theory and experimental data suggest that males and females of the same species may have divergent genetic optima, but supporting data from wild populations are still scarce. Here we present evidence for sexually antagonistic fitness variation in a natural population, using data from a long-term study of red deer (Cervus elaphus). We show that male red deer with relatively high fitness fathered, on average, daughters with relatively low fitness. This was due to a negative genetic correlation between estimates of fitness in males and females. In particular, we show that selection favours males that carry low breeding values for female fitness. Our results demonstrate that sexually antagonistic selection can lead to a trade-off between the optimal genotypes for males and females; this mechanism will have profound effects on the operation of selection and the maintenance of genetic variation in natural populations.
Mots-clé
Animals, Breeding, Deer/genetics, Deer/physiology, Female, Genetic Variation/genetics, Genotype, Male, Microsatellite Repeats/genetics, Models, Genetic, Phenotype, Reproduction/genetics, Reproduction/physiology, Scotland, Selection (Genetics), Survival Rate
Pubmed
Web of science
Création de la notice
18/03/2008 11:28
Dernière modification de la notice
03/03/2018 14:16
Données d'usage