Mechanism of analgesia induced by hypnosis and acupuncture: is there a difference?

Details

Serval ID
serval:BIB_15D089BEDBB3
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Mechanism of analgesia induced by hypnosis and acupuncture: is there a difference?
Journal
Pain
Author(s)
Moret  V., Forster  A., Laverriere  M. C., Lambert  H., Gaillard  R. C., Bourgeois  P., Haynal  A., Gemperle  M., Buchser  E.
ISSN
0304-3959 (Print)
Publication state
Published
Issued date
05/1991
Volume
45
Number
2
Pages
135-40
Notes
Clinical Trial
Controlled Clinical Trial
Journal Article --- Old month value: May
Abstract
Hypnosis and acupuncture can alleviate experimentally induced pain but the mechanism of analgesia remains unclear for both techniques. Experimental pain was induced by cold pressor test (CPT) in 8 male volunteers. Analgesic effect of hypnosis (HA) and acupuncture (AA) was assessed before and after double-blind administration of placebo or naloxone, in a prospective, cross-over study. We found that pain intensity was significantly lower with HA as compared with AA, both with naloxone (P less than 0.001) and placebo (P less than 0.001). Within HA or AA groups, pain scores did not differ significantly when naloxone or placebo was administered. During AA, however, pain scores were similar to control values when naloxone was given (P = 0.05) but decreased significantly with placebo (P less than 0.002). Analog scales for pain intensity and pain relief showed a good correlation (r = 0.94). Plasma levels of beta-endorphins did not change significantly in any combination. Heart rate, peripheral arterial blood pressure and skin conductance were very insensitive indices to assess pain intensity or relief, as well as intensity of acupuncture stimulation or depth of hypnotic trance. We conclude: (1) HA and AA can significantly reduce pain from CPT, and HA is more effective than AA: (2) HA and AA are not primarily mediated by the opiate endorphin system; and (3) plasmatic levels of beta-endorphins are not significantly affected by either HA or AA nor by naloxone or placebo administration.
Keywords
*Acupuncture Analgesia Adult Affect *Analgesia Blood Pressure Heart Rate Humans *Hypnosis Male Naloxone/pharmacology Pain/physiopathology/psychology/*therapy Pain Measurement Reference Values Skin Physiology beta-Endorphin/blood
Pubmed
Web of science
Create date
15/02/2008 16:57
Last modification date
20/08/2019 12:45
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