Downstream targets of let-60 Ras in Caenorhabditis elegans.

Détails

ID Serval
serval:BIB_11C9F0684008
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Downstream targets of let-60 Ras in Caenorhabditis elegans.
Périodique
Developmental Biology
Auteur(s)
Romagnolo B., Jiang M., Kiraly M., Breton C., Begley R., Wang J., Lund J., Kim S.K.
ISSN
0012-1606
Statut éditorial
Publié
Date de publication
2002
Peer-reviewed
Oui
Volume
247
Numéro
1
Pages
127-136
Langue
anglais
Résumé
In Caenorhabditis elegans, let-60 Ras controls many cellular processes, such as differentiation of vulval epithelial cells, function of chemosensory neurons, and meiotic progression in the germ line. Although much is known about the let-60 Ras signaling pathway, relatively little is understood about the target genes induced by let-60 Ras signaling that carry out terminal effector functions leading to morphological change. We have used DNA microarrays to identify 708 genes that change expression in response to activated let-60 Ras.
Mots-clé
Animals, Caenorhabditis elegans/embryology, Caenorhabditis elegans/genetics, Caenorhabditis elegans Proteins, Gene Expression Regulation, Developmental, Helminth Proteins/genetics, Oligonucleotide Array Sequence Analysis, Signal Transduction/genetics, ras Proteins/genetics
Pubmed
Web of science
Open Access
Oui
Création de la notice
19/11/2007 9:31
Dernière modification de la notice
20/08/2019 12:39
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