Repeated Pre-Syncope from Increased Inspired CO2 in a Background of Severe Hypoxia.

Détails

ID Serval
serval:BIB_0CA733A4E441
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Repeated Pre-Syncope from Increased Inspired CO2 in a Background of Severe Hypoxia.
Périodique
High Altitude Medicine and Biology
Auteur(s)
Fan J.L., Kayser B.
ISSN
1557-8682 (Electronic)
ISSN-L
1527-0297
Statut éditorial
Publié
Date de publication
2014
Volume
15
Numéro
1
Pages
70-77
Langue
anglais
Notes
Publication types: Journal Article , pdf : Case Reports
Résumé
We describe a case of experimentally induced pre-syncope in a healthy young man when exposed to increased inspired CO2 in a background of hypoxia. Acute severe hypoxia (FIO2=0.10) was tolerated, but adding CO2 to the inspirate caused pre-syncope symptoms accompanied by hypotension and large reductions in both mean and diastolic middle cerebral artery velocity, while systolic flow velocity was maintained. The mismatch of cerebral perfusion pressure and vascular tone caused unique retrograde cerebral blood flow at the end of systole and a reduction in cerebral tissue oxygenation. We speculate that this occurrence of pre-syncope was due to hypoxia-induced inhibition of brain regions responsible for compensatory sympathetic activity to relative hypercapnia.
Pubmed
Web of science
Création de la notice
01/05/2014 18:47
Dernière modification de la notice
03/03/2018 13:38
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