Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
A fatality involving two unusual compounds--zolpidem and acepromazine.
American Journal of Forensic Medicine and Pathology : Official Publication of the National Association of Medical Examiners
A fatality due to ingestion of zolpidem, a recently developed nonbenzodiazepine hypnotic, and acepromazine, a phenothiazine sedative used in veterinary practice, is reported. Both drugs were identified and quantified using high-performance liquid chromatography with diode-array detection. Zolpidem and acepromazine blood concentrations were 3.29 and 2.40 micrograms/ml, respectively. It is the first report of a death involving either of these two drugs. The results are discussed in the light of the existing literature and may suggest a reciprocal potentiation of the toxic effects of zolpidem and phenothiazines.
Acepromazine/blood, Acepromazine/poisoning, Adult, Bile/chemistry, Chromatography, High Pressure Liquid, Coma/chemically induced, Female, Gastrointestinal Contents/chemistry, Humans, Hypnotics and Sedatives/poisoning, Immunoassay, Pyridines/blood, Pyridines/poisoning, Suicide
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