Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
The role of botulinum toxin in neurourology.
Drugs of Today
Publication types: Journal Article ; ReviewPublication Status: ppublish
Botulinum toxin is a presynaptic neuromuscular blocking agent that induces a selective and reversible muscle weakness of up to several months when injected intramuscularly in minute quantities. Different medical disciplines have applied the toxin to treat mainly muscular hypercontraction. For neurourologically impaired patients, the reported successful treatment of neurogenic detrusor overactivity and detrusor sphincter dyssynergia with botulinum-A toxin is a promising alternative option to conservative medication or surgery. This review of the literature presents current indications, techniques for and results of the use of botulinum toxin in neurourologically impaired patients and aims to give an insight into this new therapeutic option.
Botulinum Toxins, Type A/therapeutic use, Humans, Neuromuscular Blocking Agents/therapeutic use, Randomized Controlled Trials as Topic, Spinal Cord Injuries/complications, Urethral Obstruction/drug therapy, Urethral Obstruction/etiology, Urinary Bladder, Neurogenic/drug therapy, Urinary Bladder, Neurogenic/etiology, Urinary Incontinence/drug therapy, Urinary Incontinence/etiology, Urologic Diseases/drug therapy, Urologic Diseases/etiology
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