Hamodynamische Auswirkungen der Implantation eines intrakavalen Gasaustauschers. [Hemodynamic effects of implantation of an intracaval gas exchanger]

Details

Serval ID
serval:BIB_0A079ECC72E6
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Hamodynamische Auswirkungen der Implantation eines intrakavalen Gasaustauschers. [Hemodynamic effects of implantation of an intracaval gas exchanger]
Journal
Helvetica Chirurgica Acta
Author(s)
von Segesser  L. K., Pasic  M., Lachat  M., Leskosek  B., Spiess  M., Turina  M. I.
ISSN
0018-0181
Publication state
Published
Issued date
06/1993
Volume
59
Number
5-6
Pages
887-92
Notes
English Abstract
Journal Article --- Old month value: Jun
Abstract
Treatment of severe respiratory failure by extracorporeal membrane oxygenation (ECMO) is complex. However, there is now an intravascular gas exchanger (IVOX) available that provides extrapulmonary gas transfer without requiring an extracorporeal blood path. The present study was performed to determine the hemodynamic effects resulting from the intracaval placement of the intravascular device. A bovine model (n = 6; bodyweight = 72 +/- 5 kg) was selected for temporary lung support with the intravascular device. The latter was placed in the caval axis under fluoroscopic control after full instrumentation of the animal for hemodynamic measurements including a pulmonary artery catheter for determination of cardiac output by thermodilution and continuous read out of mixed venous oxygen saturation. All measurements were taken after a stabilization period of 15 min. The heart rate moved from 65 +/- 8 before to 72 +/- 10 after implantation and 68 +/- 9 after onset of intravascular gas exchange (NS). Right atrial pressure was 13 +/- 3 mm Hg before, 12 +/- 3 mm Hg after implantation and 10 +/- 3 mm Hg after onset (NS) whereas femoral venous pressure moved from 14 +/- 3 mm Hg to 17 +/- 4 mm Hg (p < 0.05) and remained at 17 +/- 4 mm Hg after onset. Cardiac output was 5.3 +/- 0.7 l/min before, 5.4 +/- 0.7 l/min after implantation and 5.3 +/- 1.1 l/min after onset (NS) and mixed venous oxygen saturation dropped from 60 +/- 7% to 54 +/- 11% and moved to 57 +/- 11 after onset of the device (NS).(ABSTRACT TRUNCATED AT 250 WORDS)
Keywords
Animals Cattle Female Hemodynamics/*physiology Oxygen/blood *Oxygenators, Membrane *Prostheses and Implants Prosthesis Design Pulmonary Gas Exchange/*physiology Venae Cavae
Pubmed
Web of science
Create date
14/02/2008 14:17
Last modification date
20/08/2019 12:32
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