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Vascular depression. An age-related mood disorder
European Geriatric Medicine
Neuropathological and radiological evidences implicating cerebrovascular disease in the pathogenesis of certain types of geriatric depression have led to the relatively recent description of vascular depression, an age-related mood disorder. Its clinical and radiological presentation, the frequent coexistence of cognitive disorders including impairment in executive function and resistance to antidepressant therapy distinguish it from other types of depression. This article presents an overview of the existing literature on the epidemiology, pathophysiology, clinical features and therapeutic particularities of vascular depression. (C) 2010 Elsevier Masson SAS and European Union Geriatric Medicine Society. All rights reserved.
Vascular depression, Elderly, Mood disorders, LATE-LIFE DEPRESSION, WHITE-MATTER HYPERINTENSITIES, DORSOLATERAL PREFRONTAL CORTEX, SUBCORTICAL ISCHEMIC DEPRESSION, TREATMENT-RESISTANT DEPRESSION, EXECUTIVE DYSFUNCTION SYNDROME, CEREBROVASCULAR RISK-FACTORS, HEART-RATE-VARIABILITY, LATE-ONSET DEPRESSION, BRAIN-DISEASE-MODEL
Web of science
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