Article: article from journal or magazin.
Les tumeurs neuroendocrines du thymus [Thymic neuroendocrine tumors: report on 6 cases]
Annales de pathologie
PT - Case Reports PT - English Abstract PT - Journal Article
AIM: the aim of our study was to analyze a series of 6 thymic neuroendocrine tumors (TNET). METHODS: we report the clinical and pathological features of 6 TNET reclassified according to the last WHO classification (2004). RESULTS: there were 4 men and 2 women, (mean age of 61.3 years), presenting with local symptoms in 4 cases. The tumors were reclassified as 3 atypical carcinoids (AC), 2 small cell carcinomas (SCC) and 1 large cell neuroendocrine carcinoma (LCNEC). Cytokeratin, EMA and neuroendocrine markers were expressed in poorly-differentiated tumors. Two patients were lost of follow-up. Two patients with AC died of disease at 20 and 36 months. One patient with SCC died of disease at 2 years and the patient with the LCNEC died of disease in 3 months. CONCLUSION: TNET are poor prognosis tumors with a prognosis similar to thymic carcinomas. Adequate surgical resection is a strong prognosis factor
Aged/Carcinoid Tumor/Carcinoma/Carcinoma,Neuroendocrine/classification/Disease/Fatal Outcome/Female/Humans/Immunohistochemistry/Male/methods/Middle Aged/Neuroendocrine Tumors/Pathology/Prognosis/surgery/Thymus Neoplasms/Treatment Outcome
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