Current use of imaging and electromagnetic source localization procedures in epilepsy surgery centers across Europe.

Details

Serval ID
serval:BIB_004244091EBC
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Current use of imaging and electromagnetic source localization procedures in epilepsy surgery centers across Europe.
Journal
Epilepsia
Author(s)
Mouthaan B.E., Rados M., Barsi P., Boon P., Carmichael D.W., Carrette E., Craiu D., Cross J.H., Diehl B., Dimova P., Fabo D., Francione S., Gaskin V., Gil-Nagel A., Grigoreva E., Guekht A., Hirsch E., Hecimovic H., Helmstaedter C., Jung J., Kalviainen R., Kelemen A., Kimiskidis V., Kobulashvili T., Krsek P., Kuchukhidze G., Larsson P.G., Leitinger M., Lossius M.I., Luzin R., Malmgren K., Mameniskiene R., Marusic P., Metin B., Özkara C., Pecina H., Quesada C.M., Rugg-Gunn F., Rydenhag B., Ryvlin P., Scholly J., Seeck M., Staack A.M., Steinhoff B.J., Stepanov V., Tarta-Arsene O., Trinka E., Uzan M., Vogt V.L., Vos S.B., Vulliémoz S., Huiskamp G., Leijten F.S., Van Eijsden P., Braun K.P.
Working group(s)
E-PILEPSY consortium
ISSN
1528-1167 (Electronic)
ISSN-L
0013-9580
Publication state
Published
Issued date
2016
Peer-reviewed
Oui
Volume
57
Number
5
Pages
770-776
Language
english
Abstract
OBJECTIVE: In 2014 the European Union-funded E-PILEPSY project was launched to improve awareness of, and accessibility to, epilepsy surgery across Europe. We aimed to investigate the current use of neuroimaging, electromagnetic source localization, and imaging postprocessing procedures in participating centers.
METHODS: A survey on the clinical use of imaging, electromagnetic source localization, and postprocessing methods in epilepsy surgery candidates was distributed among the 25 centers of the consortium. A descriptive analysis was performed, and results were compared to existing guidelines and recommendations.
RESULTS: Response rate was 96%. Standard epilepsy magnetic resonance imaging (MRI) protocols are acquired at 3 Tesla by 15 centers and at 1.5 Tesla by 9 centers. Three centers perform 3T MRI only if indicated. Twenty-six different MRI sequences were reported. Six centers follow all guideline-recommended MRI sequences with the proposed slice orientation and slice thickness or voxel size. Additional sequences are used by 22 centers. MRI postprocessing methods are used in 16 centers. Interictal positron emission tomography (PET) is available in 22 centers; all using 18F-fluorodeoxyglucose (FDG). Seventeen centers perform PET postprocessing. Single-photon emission computed tomography (SPECT) is used by 19 centers, of which 15 perform postprocessing. Four centers perform neither PET nor SPECT in children. Seven centers apply magnetoencephalography (MEG) source localization, and nine apply electroencephalography (EEG) source localization. Fourteen combinations of inverse methods and volume conduction models are used.
SIGNIFICANCE: We report a large variation in the presurgical diagnostic workup among epilepsy surgery centers across Europe. This diversity underscores the need for high-quality systematic reviews, evidence-based recommendations, and harmonization of available diagnostic presurgical methods.
Pubmed
Web of science
Open Access
Yes
Create date
09/04/2016 15:30
Last modification date
20/08/2019 12:22
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