Plasma Membrane Domain Patterning and Self-Reinforcing Polarity in Arabidopsis.

Détails

ID Serval
serval:BIB_FF220505FD2A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Plasma Membrane Domain Patterning and Self-Reinforcing Polarity in Arabidopsis.
Périodique
Developmental cell
Auteur(s)
Marhava P., Aliaga Fandino A.C., Koh SWH, Jelínková A., Kolb M., Janacek D.P., Breda A.S., Cattaneo P., Hammes U.Z., Petrášek J., Hardtke C.S.
ISSN
1878-1551 (Electronic)
ISSN-L
1534-5807
Statut éditorial
Publié
Date de publication
27/01/2020
Peer-reviewed
Oui
Volume
52
Numéro
2
Pages
223-235.e5
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
Cell polarity is a key feature in the development of multicellular organisms. For instance, asymmetrically localized plasma-membrane-integral PIN-FORMED (PIN) proteins direct transcellular fluxes of the phytohormone auxin that govern plant development. Fine-tuned auxin flux is important for root protophloem sieve element differentiation and requires the interacting plasma-membrane-associated BREVIS RADIX (BRX) and PROTEIN KINASE ASSOCIATED WITH BRX (PAX) proteins. We observed "donut-like" polar PIN localization in developing sieve elements that depends on complementary, "muffin-like" polar localization of BRX and PAX. Plasma membrane association and polarity of PAX, and indirectly BRX, largely depends on phosphatidylinositol-4,5-bisphosphate. Consistently, mutants in phosphatidylinositol-4-phosphate 5-kinases (PIP5Ks) display protophloem differentiation defects similar to brx mutants. The same PIP5Ks are in complex with BRX and display "muffin-like" polar localization. Our data suggest that the BRX-PAX module recruits PIP5Ks to reinforce PAX polarity and thereby the polarity of all three proteins, which is required to maintain a local PIN minimum.
Mots-clé
Arabidopsis/genetics, Arabidopsis/growth & development, Arabidopsis/metabolism, Arabidopsis Proteins/genetics, Arabidopsis Proteins/metabolism, Cell Differentiation, Cell Membrane/metabolism, Cell Polarity, Gene Expression Regulation, Plant, Mutation, Paired Box Transcription Factors/genetics, Paired Box Transcription Factors/metabolism, Phosphoric Monoester Hydrolases/genetics, Phosphoric Monoester Hydrolases/metabolism, Phosphotransferases (Alcohol Group Acceptor)/metabolism, Plant Roots/genetics, Plant Roots/growth & development, Plant Roots/metabolism, Arabidopsis, DRP1A, PIP5K1, PIP5K2, endocytosis, phloem, polar auxin transport, polarity, protophloem, root
Pubmed
Web of science
Création de la notice
03/01/2020 16:52
Dernière modification de la notice
02/03/2021 12:58
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