The neural basis of temporal auditory discrimination.

Détails

ID Serval
serval:BIB_FEC9CD3DDA93
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
The neural basis of temporal auditory discrimination.
Périodique
Neuroimage
Auteur(s)
Pastor M.A., Macaluso E., Day B.L., Frackowiak R.S.
ISSN
1053-8119 (Print)
ISSN-L
1053-8119
Statut éditorial
Publié
Date de publication
2006
Volume
30
Numéro
2
Pages
512-520
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
When two identical stimuli, such as a pair of clicks, are presented with a sufficiently long time-interval between them they are readily perceived as two separate events. However, as they are presented progressively closer together, there comes a point when the two separate stimuli are perceived as one. This phenomenon applies not only to hearing but also to other sensory modalities. Damage to the basal ganglia disturbs this type of temporal discrimination irrespective of sensory modality, suggesting a multimodal process is involved. Our aim was to study the neural substrate of auditory temporal discrimination in healthy subjects and to compare it with structures previously associated with analogous tactile temporal discrimination. During fMRI scanning, paired-clicks separated by variable inter-stimulus intervals (1-50 ms) were delivered binaurally, with different intensities delivered to each ear, yielding a lateralised auditory percept. Subjects were required (a) to report whether they heard one or two stimuli (TD: temporal discrimination); or (b) to report whether the stimuli were located on the right or left side of the head mid-line (SD: spatial discrimination); or (c) simply to detect the presence of an auditory stimulus (control task). Our results showed that both types of auditory discrimination (TD and SD) compared to simple detection activated a network of brain areas including regions of prefrontal cortex and basal ganglia. Critically, two clusters in pre-SMA and the anterior cingulate cortex were specifically activated by TD. Furthermore, these clusters overlap with regions activated for similar judgments in the tactile modality suggesting that they fulfill a multimodal function in the temporal processing of sensory events.
Mots-clé
Acoustic Stimulation, Adult, Auditory Perception/physiology, Brain/physiology, Cerebral Cortex/physiology, Data Interpretation, Statistical, Discrimination (Psychology)/physiology, Echo-Planar Imaging, Female, Functional Laterality/physiology, Gyrus Cinguli/physiology, Humans, Magnetic Resonance Imaging, Male, Motor Cortex/physiology, Psychophysiology, Reproducibility of Results, Somatosensory Cortex/physiology, Sound Localization, Space Perception/physiology
Pubmed
Web of science
Création de la notice
11/09/2011 18:15
Dernière modification de la notice
20/08/2019 16:29
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