Macrophage migration inhibitory factor reduces the growth of virulent Mycobacterium tuberculosis in human macrophages

Détails

ID Serval
serval:BIB_FEA7D10E27FF
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Macrophage migration inhibitory factor reduces the growth of virulent Mycobacterium tuberculosis in human macrophages
Périodique
Infection and Immunity
Auteur(s)
Oddo  M., Calandra  T., Bucala  R., Meylan  P. R.
ISSN
0019-9567 (Print)
Statut éditorial
Publié
Date de publication
06/2005
Volume
73
Numéro
6
Pages
3783-6
Notes
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S. --- Old month value: Jun
Résumé
Macrophage migration inhibitory factor (MIF) is a key mediator of the innate immune system and plays a crucial role in the host response to bacterial infections. Its role in immunity to intracellular pathogens has not been well studied. Here, we show that MIF released by infected human macrophages inhibits the growth of virulent Mycobacterium tuberculosis.
Mots-clé
Humans Macrophage Migration-Inhibitory Factors/*physiology Macrophages/*immunology/microbiology Mycobacterium tuberculosis/growth & development/*immunology Virulence
Pubmed
Web of science
Open Access
Oui
Création de la notice
25/01/2008 14:28
Dernière modification de la notice
20/08/2019 17:29
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