Thoracic aortic dissection associated with cocaine abuse.

Détails

ID Serval
serval:BIB_FEA1859D120B
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Thoracic aortic dissection associated with cocaine abuse.
Périodique
Forensic Science International
Auteur⸱e⸱s
Palmiere C., Burkhardt S., Staub C., Hallenbarter M., Paolo Pizzolato G., Dettmeyer R., La Harpe R.
ISSN
0379-0738 (Print)
ISSN-L
0379-0738
Statut éditorial
Publié
Date de publication
2004
Peer-reviewed
Oui
Volume
141
Numéro
2-3
Pages
137-142
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article Publication Status: ppublish
Résumé
Cardiovascular complications of cocaine abuse include myocardial ischemia and infarction, dysrhythmias, cardiomyopathies and aortic dissection. The case in point pertains to a 26-year-old, Caucasian male, substance abuser who suffered a thoracic aortic dissection following the use of crack cocaine. The autopsy and histological findings showed a connective tissue abnormality including a focal microcystic medial necrosis and a fragmentation of the elastic fibers in the arterial walls. Blood concentrations of cocaine and benzoylecgonine, taken individually, were considered to be within a potentially toxic range. Blood concentrations of methadone also indicated use of this drug at the same time. The small amounts of morphine found in the blood and urine were compatible with heroine or morphine use more than 24 h before death.
Mots-clé
Adult, Aneurysm, Dissecting/etiology, Aortic Aneurysm, Thoracic/etiology, Cocaine-Related Disorders/complications, Crack Cocaine/adverse effects, Crack Cocaine/blood, Fatal Outcome, Humans, Male, Substance Abuse, Intravenous/complications
Pubmed
Web of science
Création de la notice
05/05/2015 8:12
Dernière modification de la notice
20/08/2019 16:29
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