Mastocytosis and atopy: a study of 33 patients with urticaria pigmentosa
Détails
ID Serval
serval:BIB_FD25A1AB4D7A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Mastocytosis and atopy: a study of 33 patients with urticaria pigmentosa
Périodique
Allergy
ISSN
0105-4538 (Print)
Statut éditorial
Publié
Date de publication
11/1990
Volume
45
Numéro
8
Pages
597-603
Notes
Journal Article --- Old month value: Nov
Résumé
Thirty-three patients with histologically verified urticaria pigmentosa were studied for coexisting atopic disease by means of history, skin prick testing with five common inhalants and serological investigation for total IgE and specific IgE antibodies to five common inhalants. The prevalence of atopy in urticaria pigmentosa was similar to that observed in the normal Swiss population, both on the basis of history (7/33 = 21%) and of positive skin prick tests to common inhalants (12/33 = 36%). However, total serum IgE levels were significantly lower (geometric mean value 16.8 kU/l) than in a control group of 52 Swiss blood donors of comparable age and sex distribution (geometric mean value 43.0 kU/l, t = 2.93, P less than 0.005). Specific IgE antibodies to common inhalants were also observed less frequently in urticaria pigmentosa patients than in controls, although this difference was not statistically significant. Low total and specific IgE values in patients with urticaria pigmentosa may be explained by increased absorption of circulating IgE to abundant tissue mast cells.
Mots-clé
Adolescent
Adult
Aged
Allergens/immunology
Child
Child, Preschool
Female
Humans
Hypersensitivity, Immediate/*complications/immunology
Immunoglobulin E/analysis/immunology
Infant
Male
Mastocytosis/*complications/immunology
Middle Aged
Questionnaires
Urticaria Pigmentosa/*complications/immunology
Venoms/immunology
Pubmed
Web of science
Création de la notice
28/01/2008 12:59
Dernière modification de la notice
20/08/2019 17:28