Immunite et neurodegenerescence: nouveaux concepts dans la sclerose en plaques. [Immunity and neurodegeneration: new concepts in multiple sclerosis]

Détails

ID Serval
serval:BIB_FC2B4EEC7C13
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Immunite et neurodegenerescence: nouveaux concepts dans la sclerose en plaques. [Immunity and neurodegeneration: new concepts in multiple sclerosis]
Périodique
Revue Médicale Suisse
Auteur⸱e⸱s
Lalive  P. H., Schluep  M., Chofflon  M., Du Pasquier  R.
ISSN
1660-9379 (Print)
Statut éditorial
Publié
Date de publication
05/2006
Volume
2
Numéro
64
Pages
1166-8, 1170
Notes
English Abstract
Journal Article
Review --- Old month value: May 3
Résumé
Multiple sclerosis is an autoimmune demyelinating disease of the central nervous system that leads to a progressive deterioration of the neurological functions. The concept of primary myelin and oligodendrocyte damage with axon sparing (axon-myelin dissociation) has been recently reconsidered with the demonstration that neuro-axonal lesions are an early phenomenon, linked to the inflammatory process, observed outside demyelinated areas, and correlated with the progression of the disease. Neurodegeneration in MS, long considered as a late process following recurrent episodes of demyelination, is now accepted as an early and major trigger of MS pathogenesis on which research should focus in the
Mots-clé
Humans Multiple Sclerosis/*immunology/*pathology Neurodegenerative Diseases/immunology/pathology
Pubmed
Création de la notice
25/01/2008 14:56
Dernière modification de la notice
20/08/2019 16:27
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