Multiple osteosclerotic lesions in an Iron Age skull from Switzerland (320-250 BC)--an unusual case.

Détails

Ressource 1Télécharger: smw.2013.13819.pdf (1259.47 [Ko])
Etat: Public
Version: Final published version
ID Serval
serval:BIB_FB8D7CB36BC4
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Multiple osteosclerotic lesions in an Iron Age skull from Switzerland (320-250 BC)--an unusual case.
Périodique
Swiss medical weekly
Auteur(s)
Moghaddam N., Langer R., Ross S., Nielsen E., Lösch S.
ISSN
1424-3997 (Electronic)
ISSN-L
0036-7672
Statut éditorial
Publié
Date de publication
29/07/2013
Peer-reviewed
Oui
Volume
143
Pages
w13819
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Publication Status: epublish
Résumé
The single Hochdorf burial was found in 1887 during construction work in the Canton of Lucerne, Switzerland. It dates from between 320 and 250 BC. The calvarium, the left half of the pelvis and the left femur were preserved. The finding shows an unusual bony alteration of the skull. The aim of this study was to obtain a differential diagnosis and to examine the skull using various methods. Sex and age were determined anthropologically. Radiological examinations were performed with plain X-ray imaging and a multislice computed tomography (CT) scanner. For histological analysis, samples of the lesion were taken. The pathological processing included staining after fixation, decalcification, and paraffin embedding. Hard-cut sections were also prepared. The individual was female. The age at death was between 30 and 50 years. There is an intensely calcified bone proliferation at the right side of the os frontalis. Plain X-ray and CT imaging showed a large sclerotic lesion in the area of the right temple with a partly bulging appearance. The inner boundary of the lesion shows multi-edged irregularities. There is a diffuse thickening of the right side. In the left skull vault, there is a mix of sclerotic areas and areas which appear to be normal with a clear differentiation between tabula interna, diploë and tabula externa. Histology showed mature organised bone tissue. Radiological and histological findings favour a benign condition. Differential diagnoses comprise osteomas which may occur, for example, in the setting of hereditary adenomatous polyposis coli related to Gardner syndrome.

Mots-clé
Adult, Female, Humans, Middle Aged, Neoplasms, Multiple Primary/diagnostic imaging, Neoplasms, Multiple Primary/pathology, Osteoma/diagnostic imaging, Osteoma/pathology, Paleopathology, Radiography, Skull Neoplasms/diagnostic imaging, Skull Neoplasms/pathology, Switzerland
Pubmed
Web of science
Open Access
Oui
Création de la notice
31/10/2017 11:54
Dernière modification de la notice
20/08/2019 17:26
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