Optical coherence tomography (OCT) to image active and inactive retinoblastomas as well as retinomas.

Détails

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Etat: Public
Version: Final published version
Licence: CC BY-NC-ND 4.0
ID Serval
serval:BIB_FB29F58951EE
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Optical coherence tomography (OCT) to image active and inactive retinoblastomas as well as retinomas.
Périodique
Acta ophthalmologica
Auteur(s)
Nadiarnykh O., McNeill-Badalova N.A., Gaillard M.C., Bosscha M.I., Fabius AWM, Verbraak F.D., Munier F.L., de Boer J.F., Moll A.C.
ISSN
1755-3768 (Electronic)
ISSN-L
1755-375X
Statut éditorial
Publié
Date de publication
03/2020
Peer-reviewed
Oui
Volume
98
Numéro
2
Pages
158-165
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
To illustrate Optical Coherence Tomography (OCT) images of active and inactive retinoblastoma (Rb) tumours.
Current observational study included patients diagnosed with retinoblastoma and retinoma who were presented at Amsterdam UMC and Jules-Gonin Eye Hospital, between November 2010 and October 2017. Patients aged between 0 and 4 years were imaged under general anaesthesia with handheld OCT in supine position. Patients older than 4 years were imaged with the conventional OCT (Heidelberg Engineering, Heidelberg Spectralis, Germany). All patients included were divided into two groups: active and inactive tumours (retinoma and regression patterns). Patients' medical records and OCT images were analysed during meetings via discussions by ophthalmologists and physicists.
Twelve Dutch and 8 Swiss patients were divided into two groups: 2 patients with active tumour versus 18 patients with inactive tumour. Subsequently, inactive group could be divided in two groups, which consisted of 10 patients with retinoma and 8 patients with different regression pattern types. Of all included patients, 15 were male (75%). Median age at diagnosis was 18.0 months (range 0.19-715.2 months). A total of 12 retinoblastoma (active and inactive) and 8 retinoma foci were investigated by OCT. No distinction could be made between active and inactive tumours using only OCT.
Optical coherence tomography alone cannot distinguish between active and inactive Rbs. However, handheld OCT adds useful information to the established imaging techniques in the monitoring and follow-up of retinoblastoma patients. With this study, we provide an overview of OCT images of active and inactive Rbs.
Mots-clé
optical coherence tomography, paediatric oncology, regression patterns, retina, retinoblastoma, retinoma
Pubmed
Web of science
Open Access
Oui
Création de la notice
17/09/2019 16:04
Dernière modification de la notice
30/04/2021 7:16
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