Prognostic significance of nailfold capillary microscopy in patients with Raynaud's phenomenon and scleroderma-pattern abnormalities. A six-year follow-up study.

Détails

ID Serval
serval:BIB_F89DEDBBA184
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Prognostic significance of nailfold capillary microscopy in patients with Raynaud's phenomenon and scleroderma-pattern abnormalities. A six-year follow-up study.
Périodique
Clinical Rheumatology
Auteur(s)
Zufferey P., Depairon M., Chamot A.M., Monti M.
ISSN
0770-3198
Statut éditorial
Publié
Date de publication
1992
Peer-reviewed
Oui
Volume
11
Numéro
4
Pages
536-541
Langue
anglais
Notes
Publication types: Journal Article
Résumé
The aim of this study was to assess the prognostic significance of scleroderma capillary pattern (SD-pattern) in patients with Raynaud's phenomenon. Thirty patients with a capillaroscopy examination suggestive of scleroderma (megacapillaries and/or avascularity) but without clinical criteria of scleroderma (ARA criteria) were reevaluated 6 years after the initial clinical and capillaroscopy examinations. SD-pattern abnormalities were classified according to a semiquantitative method. Eight out of the 28 evaluated patients (28%) developed a scleroderma spectrum disorder (SDS). The presence of avascularity and/or a mean of more than two megacapillaries digit greatly enhanced the percentage of evolution toward SDS (70%/88% respectively). Most of the patients with few enlarged capillaries and no capillary rarefaction at entry had primary acrocyanosis (11/15). None of them developed SDS. The microangiopathy disappeared during the follow-up period in most of these patients (14/15). These results confirm the prognostic value of SD-pattern capillary abnormalities for SDS. Primary acrocyanosis, a benign clinical entity should be considered in presence of few megacapillaries and without capillary rarefaction.
Mots-clé
Aged, Capillaries, Female, Follow-Up Studies, Humans, Male, Middle Aged, Nails, Prognosis, Raynaud Disease, Scleroderma, Systemic
Pubmed
Web of science
Création de la notice
25/03/2009 11:50
Dernière modification de la notice
20/08/2019 16:24
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