No benefit of longer eradication therapy of Pseudomonas aeruginosa primoinfections in pediatric cystic fibrosis
Détails
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Etat: Public
Version: Après imprimatur
Licence: Non spécifiée
ID Serval
serval:BIB_F7EF24D12187
Type
Thèse: thèse de doctorat.
Collection
Publications
Institution
Titre
No benefit of longer eradication therapy of Pseudomonas aeruginosa primoinfections in pediatric cystic fibrosis
Directeur⸱rice⸱s
HAFEN Gaudenz
Codirecteur⸱rice⸱s
AUBERT John-David
Détails de l'institution
Université de Lausanne, Faculté de biologie et médecine
Statut éditorial
Acceptée
Date de publication
2019
Langue
anglais
Résumé
Abstract
Objective: Patients with cystic fibrosis are more susceptible than members of the general population to lung infections.
Infections with Pseudomonas aeruginosa require particular attention, because they may accelerate the deterioration of lung function if not adequately treated. This study assessed the eradication rate of P. aeruginosa primoinfections, with a protocol of inhaled tobramycin and oral ciprofloxacin over a 3 months’ period.
Results: Retrospective single-center study from June 1st, 2007 to December 31st, 2015. Inclusion of 28 pediatric patients (11 females, 17 males), with a total of 49 primoinfections. Overall success rate of 67.3%, which is similar or even inferior to figures published in the literature.
Objective: Patients with cystic fibrosis are more susceptible than members of the general population to lung infections.
Infections with Pseudomonas aeruginosa require particular attention, because they may accelerate the deterioration of lung function if not adequately treated. This study assessed the eradication rate of P. aeruginosa primoinfections, with a protocol of inhaled tobramycin and oral ciprofloxacin over a 3 months’ period.
Results: Retrospective single-center study from June 1st, 2007 to December 31st, 2015. Inclusion of 28 pediatric patients (11 females, 17 males), with a total of 49 primoinfections. Overall success rate of 67.3%, which is similar or even inferior to figures published in the literature.
Mots-clé
Cystic fibrosis, Pseudomonas aeruginosa, Primoinfection, Eradication protocol
Création de la notice
15/08/2019 12:38
Dernière modification de la notice
30/10/2023 9:50
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